The client in this case study had a concern with having a BRCA1 gene mutation previously identified, which is associated with an increased risk of breast and ovarian cancer. She has two relatives in the past diagnosed with breast cancer, so reported this being a factor of her psychological stress.
The client's yearly stem cells divisions (TruAge Mitotic Clock Report) fell into the normal range, which gave her some positive reassurance about any immediate risk. But in addition to this, her markers of chronic inflammation were high. Her plan moving forward was to address the chronic inflammation, while making dietary interventions for modulating BRCA gene expression.
She increased her dietary intake of:
Polyphenol-rich foods
Sulforaphane
Curcumin
Ellagic acid
EGCG
Genistein
Omega 3
Allicin
Where certain dietary changes were hard to maintain, supplements were added in. In response to OMICm Clock biomarkers and a corresponding blood test, vitamin B12, folate, and iron supplements were also incorporated.
Steps were made to lower her average fasting glucose and HBA1c level. She reduced her weekly alcohol consumption by around 30%, while lowering other toxin exposures and inflammatory food sources. Her diet changes were aimed to increase phase 1 detoxification, with certain supplements to increase phase 2 detoxification, on top of sauna usage.
To promote a more alkaline bodily state, her animal protein intake was roughly halved, with the added benefit of cutting down the amino acid L-methionine for slowing cellular proliferation.
After six months, her markers of oxidative stress and inflammation went down, these include DNAm: red cell distribution width, IGFBP-2, carotene diol, gluconate, telomere length, IL-6, and CRP.
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